N.O. Spot covers all aspects of training with a tri-phase formula that addresses the three critical components of any exercise regimen; energy&focus, nutrients to prime and build muscle, and nitric oxide boosting amino acids.
Energy and Focus
N.O. Spot has a unique energy and focus blends that takes an efficient dose -275mg- of caffeine anhydrous combined with catecholamine reuptake inhibitors N-acetyl-l-tyrosine and Methylliberine (as pure Dynamine™) to provide euphoric energy, mood, and focus increases. The caffeine is a fast-acting stimulant that increases energy levels by blocking adenosine receptors from being bound by adenosine- this compound is responsible for fatigue. The catecholamine reuptake inhibitors work to block transport proteins of catecholamines (dopamine, norepinephrine, epinephrine) in the neural synapse. By blocking these proteins, the catecholamines avoid being taken out of the synapse to be recycled for a short time longer than usual (not all of the neurotransmitters, just more than usual) which allows them to exert their effects as energy, mood, and focus increasers more effectively. The combinations of these two classes of compounds allows for effective energy and focus, while eliminating the need for massive doses of caffeine that causes negative side effects and severe crashes.
N.O. Spot provides nutrients your body needs to build muscle but usually lacks effective doses of when relying on diet alone. Taken pre-workout, these nutrients are readily available in your system when undergoing physical activity, allowing your muscle cells to effectively absorb and utilize them when needed. We utilize three different compounds to achieve this:
Cluster Dextrin™: A supercarb source that is derived from amylopectin (starch) via a cyclization reaction to produce highly-branched-cyclic-dextrin molecules. This unique structure is your bodies preferred source of ATP(D-glucose) in a configuration that allows it to past through the stomach and into the small intestines within 20 minutes. There your body can absorb it and generate the ATP needed to blast through workouts
Betaine: Betaine is a compound derived from the amino acid choline and shown to have positive effects as a performance enhancer due to it’s role in acting as an indirect methyl group donor in biological processes and aiding in osmolarity of the cell.
BCAAs: BCAAs are the most abundant amino acids in muscle tissue and are the most readily absorbed group of amino acids due to their aliphatic side chain that contains a branch. Intra-Fuel contains a Leucine favored ratio of 2 parts Leucine to 1 part Isoleucine and Valine as Leucine is found most abundantly and has been shown to stimulate the mTOR pathway for increasing protein synthesis. These amino acids increase protein synthesis and nitrogen retention, both essential to buildng lean muscle. BCAAs are metabolized directly in the muscle and are considered “essential” because the body cannot build them from other compounds. Instead they must come from diet or supplementation.
Nitric Oxide/Pump Matrix
Beta-Alanine: a unique compound as it's the beta form of the amino acid L-alanine. This means the NH3+ group on the amino acid is bonded to the beta carbon and not the alpha carbon, allowing it to serve different functions than regular L-alanine. Muscle tissue utilizes bet-alanine by combining it with L-histidine to form carnosine, a compound that buffers (neutralizes) acids. When undergoing strenuous exercise, cellular pH tends to become more acidic due to byproducts formed by the process of making ATP. The more readily available beta-alanine you have before exercise, the more carnosine your body will be able produce while working out. The longer you can keep your cellular pH in normal range, the longer you'll delay fatigue.
Citrulline Malate: L-Citrulline is one of the three dietary amino acids that are involved in the urea cycle working in conjunction with L-Arginine and L-Ornithine. In your kidneys, the Citrulline is converted into the products L-Arginine and nitric oxide. Nitric oxide is critical in increasing physical performance as it relaxes blood vessels, helping them to dilate and force oxygen and nutrient rich blood to the muscles delaying fatigue and aiding repair
Arginine AKG: Arginine AKG is a mixture containing both of the following compounds; A semi-essential amino acid (L-Arginine) and the nitrogen free form of the amino acid and glutamate (AKG). AKG stands for Alpha-ketoglutarate, which is the anion (negatively charged) version of Alpha-ketoglutaric acid. This compound is one of two ketone derivatives of glutaric acid (the other being β-ketoglutaric acid which only differs by the position of the ketone group being on the beta carbon). They both play an important role in performance enhancing an overall wellness.
Taurine: Taurine is a unique compound in the body and is often referred to as an amino acid although it technically isn’t; it is actually a by product of the amino acids cysteine and methionine. Taurine is what is known as an amino sulfonic acid as it does not contain a carboxy group (a carbon double bonded to an oxygen and single-bonded to an OH) but contains a sulfur molecule instead making it more acidic. Taurine is found in many places throughout the body and contributes to vital functional processes.